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Jo Waller's avatar

yes how many people understand this ‘T-index takes into account the avidity of the NTD for lipid raft gangliosides (ΔGmut/ΔGwt [NTD-ganglioside]), the affinity of the RBD for ACE-2 (ΔGmut/ΔGwt [RBD-ACE-2]), and a global estimation of the electrostatic surface potential of both the NTD and the RBD (kinetic parameter). Values of T-index ranged from 2.16 for the Wuhan B.1 strain to 10.67 for the India B.1.617 variant (ca. 500% increase of transmissibility)???? from a paper in August https://georgiedonny.substack.com/p/the-dangers-of-using-computer-modelling

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